In the Leading Edge Forum we believe that business and IT are now co-evolving, each developing and changing under the influence of the other in a complicated process that is often impossible to take apart. This overall point of view was laid out in a recent LEF Position Paper. Previous LEF reports have explored many of the IT industry pressures that are continually re-shaping the role of the enterprise IT function; this report focuses on the key business drivers that will increasingly determine the IT change agenda.